AromActive and Metabolic Wellness

The natural healing dietary benefits of AromActive tea likely lie in the combination of many different components, not due to one particular component.  Here are some well-researched effective molecules in the AromActive:

  1. D-chiro-inisotol (DCI) - accelerate glucose disposal, sensitize insulin action, and lower blood pressure

AromActive buckwheat flower with D-chiro-inisotol

Molecular formula:  C6H12O6

 

Molar mass: 180.16 g/mol

 

DCI is known to be an important secondary messenger in insulin signal transduction (1).  Early study demonstrated a linear relationship between its decreased urinary excretion and the degree of insulin resistance present. When tissue contents, including muscle, of type 2 diabetic subjects were assayed, they demonstrated a more general body deficiency of DCI in type 2 diabetic patients.  Administration of D-chiro-inositol to diabetic patients accelerated glucose disposal and sensitized insulin action (1)

 

The metabolic effects of D-chiro-inositol in the polycystic ovary syndrome (PCOS) patients include lowered blood pressure, increased insulin sensitivity and a corresponding improvement in glucose disposal (2).

DCI could also play a role in hunger-quenching effect.  If someone is insulin resistant, which leads to hungry cells, they may be sending your body a message to eat.  DCI can increase insulin sensitivity, which results in improved glucose uptake and utilization by the cells, and consequently quenching the hungry signal from the cells.

DCI is not abundant in most diets, and it can be found in significant quantities in tartary black bitter buckwheat as the major natural source of DCI.

The metabolic, prediabetes, and diabetes wellness benefits of tartary black bitter buckwheat (also referred as Soba in Japanese), were known in ancient Mongolia, China, Russia, and India.  Buckwheat tea (or Soba Cha) drink is a wellness tradition in many Asia countries.  Modern science has shed some lights on understanding the ancient mystery behind its natural dietary remedy benefits.  In a large epidemiology study involving 3542 Mongolians, it was found that the prevalence rates of hypertension, dyslipidaemia, and diabetes are significantly lower in participates with lifetime consumption of buckwheat seed as a staple food compared to participants who consumed corn as a staple food (6).

  1. Rutin and flavonoids – Anti-oxidant, natural blood thinner, prevent heart attack and stroke.

AromActive buckwheat flower with rutin

Molecular formula: C27H30O16

 

Molar mass: 610.52 g/mol

 

 

Rutin is an example of the abundant anti-oxidant flavonoids in AromActive.

Rutin is a strong anti-oxidant (4).  In humans, it attaches to the iron ion Fe2+, preventing it from binding to hydrogen peroxide, which would otherwise create a highly reactive free radical that may damage cells.

Rutin inhibits platelet aggregation (5), making the blood thinner and improving circulation.  Rutin could help prevent blood clots, so could be used to treat patients at risk of heart attacks and strokes.

  1. AromActive for hunger-quenching, appetite-control, and weight-control.

Over-weight has been associated as a key risk factor for diabetes and cardiovascular diseases.  Studies show that people at high risk for diabetes (e.g. prediabetes) can prevent or delay the onset of the disease by losing 5 to 7 percent of their weight, if they are overweight-that's 10 to 14 pounds for a 200-pound person.  AromActive is often used as part of a weight loss diet plan to quench hunger naturally.  Its high protein and mineral content helps curb appetite by making you feel fuller, longer.  Research indicates that AromActive ingredient (tartary black bitter buckwheat) slows down the rate of glucose absorption in the body (7), and maintains balanced blood sugar levels for a longer period of time keeps you feeling full.  By drinking AromActive before a meal and regularly, you may end up eating less and experiencing a higher level of satisfaction.

  1. Other components and functions

The health benefits of AromActive also come from its linoleic acid, essential amino acids and vitamins (B1, B2, B3, B5, E, P).  Buckwheat is also rich in the minerals chromium, copper, manganese and folic acid.  It is also a great source of magnesium. Research studies confirm that chromium can help to control blood sugar levels.  Chromium acts on insulin by binding tightly to it and causing important changes in its spatial arrangement and clumping. As a result, chromium enhances insulin activity in several ways, including: assists insulin in helping your cells take glucose in, improves the ability of your cell receptors to respond to insulin and improves glucose transport into cells (8).  Similar to DCI, by increasing cell’s sensitivity to insulin, Chromium could also help quenching the hungry signal.

AromActive is high on soluble fiber that keeps the digestive tract running smoothly, which also aids in the elimination of fat which helps decrease cholesterol and prevent arthrosclerosis. High-fiber foods also take longer to fully digest than other foods, so you will feel full for a longer period after eating.

Due to the number of B vitamins in AromActive, it is highly recommended for people who suffer from disorders of the liver and diabetes. AromActive is also low in natural sugar, which makes it perfect for people who need to monitor their sugar intake.

Salicylaldehyde (2-hydroxybenzaldehyde) was identified as a characteristic component of AromActive aroma (9). 2,5-dimethyl-4-hydroxy-3(2H)-furanone, (E,E)-2,4-decadienal, phenylacetaldehyde, 2-methoxy-4-vinylphenol, (E)-2-nonenal, decanal and hexanal also contribute to its aroma (10).  The unique AromActive aroma makes people feel full and satisfied, and could help suppress the cravings that so often sabotage a diet.

>> Learn more about the AromActive process on making the AromActive™ tea.

References:

  1. Larner J (2002). "D-chiro-inositol--its functional role in insulin action and its deficit in insulin resistance". Int. J. Exp. Diabetes Res. 3 (1): 47–60.
  2. Nestler JE etc. (2000). "Role of inositolphosphoglycan mediators of insulin action in the polycystic ovary syndrome". J. Pediatr. Endocrinol. Metab. 13. Suppl 5: 1295–8.
  3. Kreft S etc. (1999). "Extraction of rutin from buckwheat (Fagopyrum esculentum Moench) seeds and determination by capillary electrophoresis". J. Agric. Food Chem. 47 (11): 4649–52
  4. Metodiewa, D etc. (1997). "Evidence for antiradical and antioxidant properties of four biologically active N,N-Diethylaminoethyl ethers of flavaone oximes: A comparison with natural polyphenolic flavonoid rutin action". IUBMB Life 41 (5): 1067
  5. Navarro-Núñez; etc. (2008). "Apigenin Inhibits Platelet Adhesion and Thrombus Formation and Synergizes with Aspirin in the Suppression of the Arachidonic Acid Pathway". J. Agric. Food Chem. 56 (9): 2970–6.
  6. Zhang H. etc.  (2007) “Comparison of Hypertension, Dyslipidaemia and Hyperglycaemia between Buckwheat Seed-consuming and Non-consuming Mongolian-Chinese Populations in inner Mongolia, China”.  Clinical and Experimental Pharmacology and Physiology. 34(9): 838–844
  7. Berti C. etc. (2005)  “Effect on appetite control of minor cereal and pseudocereal products.”. Br J Nutr. 94(5):850-8.
  8. Hua Y. etc. (2012) “Molecular Mechanisms of Chromium in Alleviating Insulin Resistance”. J Nutr Biochem. 23(4): 313–9.
  9. Janes D. etc. (2008). "Salicylaldehyde is a characteristic aroma component of buckwheat groats". Food Chemistry 109 (2): 293–8.
  10. Janes D. etc. (2009). "Identification of buckwheat (Fagopyrum esculentum Moench) aroma compounds with GC-MS". Food Chemistry 112 (1): 120–4.

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